Description
At St. Jude Children’s Research Hospital, we stand at the forefront of biomedical research, seamlessly bridging basic science with innovative treatments for catastrophic pediatric diseases.
We are seeking the next generation of talented biomedical scientists to train at our world-class research center. We provide an outstanding training environment with support tailored to postdocs and a competitive salary starting at $72,500 per year. Current biophysical postdoc opportunities are outlined below. Please visit www.stjude.org/postdoc for additional details. Our applicant-friendly process allows multiple faculty members to view your CV – simply email your CV to postdoc@stjude.org and indicate your interest in one or more of these exciting opportunities.
Taosheng Chen, PhD, Department of Chemical Biology and Therapeutics
Study the regulation of nuclear receptors like PXR and CAR or enzymes like CYP3A4 and CYP3A5 by developing or characterizing novel chemical probes (i.e., small-molecule inhibitors or degraders).
Bryan Gibson, PhD, Department of Cell and Molecular Biology
Investigate how biomolecular phase transitions guide higher-order genome structure and influence diseases by combining biochemistry, genomics, cellular engineering, and advanced microscopy techniques to build and perturb chromatin condensates in vitro and in cells.
Tanja Mittag, PhD, Department of Structural Biology
Work on the biophysics of sequence–structure–function relationships of intrinsically disordered protein regions (IDRs) by defining sequence-encoded conformational preferences, driving force for phase separation, and emergent properties of other types of IDR sequences.
Ji Sun, PhD, Department of Structural Biology
Investigate LRRK2 signaling pathways in healthy and Parkinson’s disease (PD) conditions with cryo-EM structural studies and identify novel therapeutic strategies for PD.
Jae Yang, PhD, Department of Structural Biology
Apply multi-modal correlative imaging techniques (in situ cryo-ET and 2D/3D multimodal cryo-CLEM) and molecular biology approaches to study cell-cell and host-virus interactions in tumorigenesis and cancer treatments.
Stanislav Zakharenko, MD, PhD, Department of Developmental Neurobiology
Understand the behavior in mouse models with 22q11 and 3q29 deletion syndromes (that have high genetic risks of developing psychiatric disorders, especially schizophrenia) at the levels of neural circuits, individual neurons, synapses, and molecules by conducting 2-photon laser-scanning microscopy imaging of neuronal activity in awake mice.
Requirements
PhD in a related field.
