Description

Postdoctoral Scholar | RNA Biology/Chromatin Biology | Nazim Lab | CWRU

The laboratory of Dr. Mohammad Nazim in the Department of Biochemistry at Case Western Reserve University School of Medicine is seeking highly motivated postdoctoral researchers to investigate the regulation of post-transcriptional RNA processing and gene transcription in the chromatin. Specific projects include, but are not limited to, studying the mechanisms of pre-mRNA alternative splicing, the functional roles of alternative splice variants of chromatin regulators in cellular development, and how RNA splicing is disrupted in human diseases such as neurodevelopmental disorders and cancer. The Nazim Lab employs a variety of cell culture systems, mouse models, and molecular and genomic approaches to address key questions in RNA biology, chromatin regulation, and gene transcription, with a focus on mammalian neuronal development. We are seeking curious and dedicated researchers to join our highly collaborative and dynamic team. In addition to conducting research, postdoctoral fellows will have opportunities for career development, presentation of research at national and international conferences, mentoring students, and engaging in scientific outreach.

Requirements

Responsibilities and Duties:

The candidate will employ a combination of cell culture models, mouse models, and a range of molecular biology and biochemical assays to address questions at the intersection of RNA processing, chromatin regulation, and gene transcription. The lab aims to uncover how RNA splicing influences gene regulation in chromatin during cellular and tissue development, and how misregulation of these processes contributes to human diseases.
The successful candidate will independently plan and execute experiments to achieve research objectives and will have the opportunity to develop new and independent research directions that build upon the lab’s expertise in RNA and chromatin biology.
The position requires high scientific integrity, strong organizational skills for maintaining scientific records, respect for others, a collaborative mindset, and a commitment to learning. The successful candidate will present data in lab meetings, journal clubs, departmental seminars, and scientific conferences, and will contribute to manuscript preparation and the generation of preliminary data for grant proposals.

Minimum Qualifications:

Ph.D., M.D., or M.D./Ph.D. degree in biochemistry, molecular biology, cell biology, or a related field
A strong background in molecular biology and/or molecular genetics, experience with in vitro and/or in vivo models, and proficiency in computational biology. 
Published in internationally recognized peer-reviewed journals.
Excellent written and oral communication skills necessary.
Must be eligible to work in the United States.
 

How to Apply: 

Interested candidates should apply though the following link:

https://apply.interfolio.com/177318 

or send a current CV, a 1-page cover letter describing current and future research interests, and names and contact information for 3 references to: 

Dr. Mohammad Nazim, Assistant Professor of Biochemistry at mxn598@case.edu

Review of applications will begin immediately.

In compliance with the City of Cleveland’s Pay Transparency Ordinance (effective October 27, 2025), the annual starting base salary range for this position is $55,000 - $62,652. CWRU considers factors such as (but not limited to) the specific grant funding and the terms of the research grant when extending an offer. Postdocs receive individual and family healthcare benefits, life insurance, and employee assistance.

Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities Applications requiring a reasonable accommodation for any part of the application and hiring process should contact the CWRU Office of Equity at 216.368.3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.